Asante Kotoko FC VS Bechem United FC November 07 2021, 16:00
Bibiani Gold Stars FC VS Asante Kotoko FC November 12 2021, 15:00
Legon Cities FC VS Asante Kotoko FC November 18 2021, 15:00
Asante Kotoko FC VS Eleven Wonders November 20 2021, 15:00
Karela FC VS Asante Kotoko FC November 27 2021, 15:00
Asante Kotoko FC VS King Faisal Babies December 04 2021, 15:00
Hearts of Oak SC VS Asante Kotoko FC December 11 2021, 15:00
Asante Kotoko FC VS Real Tamale United December 15 2021, 15:00
Asante Kotoko FC VS West Africa Football Academy December 25 2021, 15:45
Aduana Stars FC VS Asante Kotoko FC January 01 2022, 15:00
Asante Kotoko FC VS Ashanti Gold Sporting Club January 08 2022, 15:00
Berekum Chelsea FC VS Asante Kotoko FC January 15 2022, 15:00
Asante Kotoko FC VS Medeama SC January 22 2022, 15:00
Asante Kotoko FC VS Accra Great Olympics January 29 2022, 15:00
Elmina Sharks FC VS Asante Kotoko FC February 05 2022, 15:00
Asante Kotoko FC VS Accra Lions FC February 12 2022, 15:00
Asante Kotoko FC VS Dreams FC February 26 2022, 15:00
Bechem United FC VS Asante Kotoko FC March 05 2022, 15:00
Asante Kotoko FC VS Bibiani Gold Stars FC March 12 2022, 15:00
Eleven Wonders VS Asante Kotoko FC March 19 2022, 15:00